Effect of Various Plant Oil and Fat on Some Biochemical Parameters in Mice
Abstract
The research's goal is to see how various high-fat diet types affected mice's lipid profiles. The study included six dietary groups of mice: the first group has been provided with a standard diet control group (G1), the second group was fed sunflower oil (20% wt/wt fat), the third group was fed corn oil (20% wt/wt fat), the fourth group was fed coconut oil (20% wt/wt fat), the fifth group was fed olive oil (20% wt/wt fat), and the sixth group was fed beef tallow (20% wt/wt fat) (G6). Low-density lipoprotein (LDL-C) and total cholesterol (TC) levels have been found to be significantly higher (P≤0.05) in groups of mice deal with corn oil, sunflower oil, and beef tallow, whereas high density lipoprotein (HDL-C), triglycerides (TG), and very low-density lipoprotein (VLDL-C) levels have not been affected. In addition, in comparison with the control group, there is a substantial (P≤0.050) drop in LDL-C in group (G5) dealing with olive oil and group (G4) dealing with coconut oil. Also there is decrease significance (P≤0.050) in total protein (TP), albumin and globulin in (G2), (G3) and (G6) compared with control group, whereas increase significance (P≤0.050) in (TP), albumin and globulin in (G5) compared with control group.In addition to increase significance (P≤0.050) in malondialdehyde (MDA) and decrease significance (P≤0.050) in glutathione (GSH) (G2), (G3) and (G6), whereas decrease significance (P≤0.050) in (MDA) and increase significance in (GSH) in (G5) compared with control group.
Full Text: PDF DOI: 10.15640/ijhs.v10n1a2
Abstract
The research's goal is to see how various high-fat diet types affected mice's lipid profiles. The study included six dietary groups of mice: the first group has been provided with a standard diet control group (G1), the second group was fed sunflower oil (20% wt/wt fat), the third group was fed corn oil (20% wt/wt fat), the fourth group was fed coconut oil (20% wt/wt fat), the fifth group was fed olive oil (20% wt/wt fat), and the sixth group was fed beef tallow (20% wt/wt fat) (G6). Low-density lipoprotein (LDL-C) and total cholesterol (TC) levels have been found to be significantly higher (P≤0.05) in groups of mice deal with corn oil, sunflower oil, and beef tallow, whereas high density lipoprotein (HDL-C), triglycerides (TG), and very low-density lipoprotein (VLDL-C) levels have not been affected. In addition, in comparison with the control group, there is a substantial (P≤0.050) drop in LDL-C in group (G5) dealing with olive oil and group (G4) dealing with coconut oil. Also there is decrease significance (P≤0.050) in total protein (TP), albumin and globulin in (G2), (G3) and (G6) compared with control group, whereas increase significance (P≤0.050) in (TP), albumin and globulin in (G5) compared with control group.In addition to increase significance (P≤0.050) in malondialdehyde (MDA) and decrease significance (P≤0.050) in glutathione (GSH) (G2), (G3) and (G6), whereas decrease significance (P≤0.050) in (MDA) and increase significance in (GSH) in (G5) compared with control group.
Full Text: PDF DOI: 10.15640/ijhs.v10n1a2
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