International Journal of Health Sciences

Evaluation the Effects of Aluminium Phosphid on Testicular Histomorphometric in Adult Rat
Nasibeh Fathi, Morteza Hajihossini, Mehdi Hatami, Akram Ranjbar

Abstract
Aluminium phosphide (ALP) is available in the form of tablets or pellets. Tablets are dark brown or grayish in color and ALP poisoning was found to be the most common cause of acute poisoning in India. The aim of this study was to evaluate the effect of ALP poisoning on spermatogenic cells. This study was performed on 14 male wistar that rats divided into 2 groups of 7 rats per group. For experimental groups was regularly fed ALP for 24hour in 2 mg/kg concentration. Treatment was carried out for 24 hours. Histological evaluation on testis section was performed using tissue processing and hematoxylineosin stainig and parameters of seminiferous tubules in testes. The result indicated that there were no significant differences between groups for spermatogonia, spermatocytes, spermatid, sertoli, leydig cells number and also in diameter, circumference and area of seminiferous tubules in experimental group when compared with control group. We canclued that ALP have not significant differences in low dose on reproductive system, it may have histopathological changes in upper dose on reproductive system, more experimental investigation are necessary to do.

Full Text: PDF     DOI: 10.15640/ijhs.v4n1a10