International Journal of Health Sciences

A Review: Proteins Involved in the Major Symptoms of Polycystic Ovarian Syndrome
Prajna Bhandary, Prakash Patil, Suchetha Kumari N, Reshma A. Shetty

Abstract
Polycystic ovary syndrome (PCOS) is an endocrine, metabolic, reproductive disorder affects around 6.5 - 18% of women at the reproductive age. Since symptoms are not universal in all patients its diagnosis has become more controversial. There are various physical and internal symptoms of PCOS such as irregular menstrual cycles, infertility, obesity, insulin resistance, hirsutism, acne, alopecia. Hyperandrogenism can be regarded as one of the culprits behind all the symptoms, whereas the study of proteins with respect to a symptom is lacking, so the present review is focused on the involvement of some proteins in the pathogenesis of PCOS. So, working in deep with these aspects will be useful in the future to better understand the biochemical, physiological, and immunological aspects and to identify the diagnostic biomarkers of PCOS and for the better therapeutic approach.

Full Text: PDF     DOI: 10.15640/ijhs.v10n1a1