International Journal of Health Sciences

Procalcitonina como Biomarcador Predictor de Mortalidad
Esthela Tinoco, María Dolores Suárez, Wendy Wasbrum, Stefany Salazar, Samanta Mite

Abstract
It is highlighted the usefulness of Procalcitonin (PCT) as a biomarker for the diagnosis of sepsis, its correlation with the extension reached by the bacteria and severity of the patient. Objective: analysis of panic values of serum Procalcitonin and the mortality rate. Methodology: Prospective cohort study of discrimination, observational study, carried out in Hospital Teodoro Maldonado, year 2017. The sample was based on 77 patients, aged 17 to 90 years, whose values were greater than 2.0 PCT., once obtained through the laboratory system, using advanced technology Data Lab Electrochemiluminiscence Elecsys. About the PCT and its classification were only used data from the values of panic. Results: PCT of most often reached ≥10 ng/ml, with an average of 57.4 ng/ml, mortality rate (39%), had a predominance of males (60%), pathological of higher frequency, Diabetes Mellitus (20%), Cancer (17%), Chronic Renal Insufficiency (17%), with a range of age between 70-79 years (30%). Discussion: In the elderly, the inflammatory response may be modified, and the comorbidities associated mainly diabetes influence the result. Conclusion: procalcitonin is not only a marker of sepsis, but also of systemic disease, which is associated with high rates of mortality; its interpretation must always confront patient history, clinical analysis, as well as results of other tests.

Full Text: PDF     DOI: 10.15640/ijhs.v6n3a3